SpliceCD19

Alternative splicing of CD19 mRNA in pediatric leukemia and CART-19 therapy resistance-regulators, genetic variants, and cryptic isoforms

Funding period:

01.11.2021 - 31.10.2024

Project description:

The project will combine high-throughput experiments, bioinformatics analysis and mathematical modeling to derive a molecular understanding of CART19 therapy resistance. This will derive prognostic biomarkers and targets of combination therapy.

Project coordination

This image shows Stefan Legewie

Stefan Legewie

Prof. Dr.

Member of the SRCSB Board of Directors

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